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Apremilast 20 mg
Price range: AUD110.00 through AUD410.00 (-27%)
| Active Ingredient | Apremilast |
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Dosage | 20 mg |
| Packaging | 4 Tablet/s in a strip |
| Delivery Time | 6 to 15 working days |
Apremilast 20 mg Australia
Apremilast 20 tablets are used to treat moderate to severe psoriasis vulgaris (a type of skin disease). This medication is used when standard treatments are ineffective or cannot be used due to side effects or poor response.
Apremilast 20 tablets can be taken with or without food. Do not stop taking the medication unless directed by your doctor, even if your symptoms improve. Take the medication regularly. This medication may cause weight loss, so you should monitor your weight regularly while taking it.
Apremilast tablets may cause common side effects such as nausea, diarrhea, vomiting, headache, and upper respiratory tract infections. If these effects continue or grow more severe, it is advisable to consult your doctor. Your doctor may be able to alleviate or prevent these symptoms by prescribing an alternative medication or adjusting the dosage.
To ensure that this medication is safe for you, tell your doctor about all medications you are currently taking before taking apremilast 20 tablets. Be sure to tell your doctor if you have any kidney, liver, heart, or other medical conditions. If you are expecting a baby or currently breastfeeding, discuss with your doctor before taking this medicine.
Use of Apremilast 20 mg Tablets
Plaque Psoriasis
Plaque psoriasis is considered the typical and most common presentation of psoriasis. Psoriasis is a disease in which skin cells proliferate excessively, resulting in scaly, dry patches. These patches can appear anywhere on the body, but are most commonly found on the scalp, elbows, knees, and hips. Apremilast 20 tablets relieve scaly, itchy patches that appear on various parts of the body. It may take several months for the full effects of the medication to become apparent. Avoid alcohol and drink plenty of water to stay hydrated during treatment.
How to Take Apremilast 20 mg Tablets
Use this medication exactly as your doctor recommends, at the specified dose and for the prescribed period. The tablet should be swallowed whole and not chewed, crushed, or divided. Apremilast 20 tablets can be taken regardless of food intake.
Mechanism of Action of Apremilast 20 mgTablets
Apremilast 20 tablets are a phosphodiesterase-4 (PDE4) inhibitor. It alleviates symptoms of psoriatic arthritis and psoriasis by inhibiting the action of specific chemical mediators that cause inflammation associated with psoriasis.
Side Effects
Most side effects do not require treatment and will subside as the body adjusts to the medication. If symptoms persist or are concerning, consult your doctor.
Common Side Effects of Apremilast
- Diarrhea
- Nausea
- Vomiting
- Headache
- Upper Respiratory Tract Infection
Safety Precautions
Alcohol
The safety of drinking alcohol while taking Apremilast 20 tablets has not been established. Consult your doctor.
Pregnancy
The safety of Apremilast tablets during pregnancy has not been established. Adequate and sufficient controlled studies in pregnant women have not been conducted, and data on reproductive toxicity in animals are insufficient. A doctor should consider the benefits and potential risks before prescribing this medication.
Breastfeeding
Information on the use of Apremilast tablets while breastfeeding is not available. Consult your doctor.
Driving
Apremilast tablets usually do not affect driving ability.
Kidney
Apremilast tablets should be administered cautiously to patients with severe kidney disease. Dose adjustment may be necessary.
Liver
Apremilast tablets can be safely used in patients with liver disease. Dose adjustment is not recommended.
If I miss a dose of Apremilast tablets, what should I do?
Take any missed Apremilast 20 tablet as soon as possible. If it is almost time for your next dose, omit the missed dose and continue with your standard schedule. Do not take a double dose.
FAQ’s
Is Apremilast 20 an immunosuppressant?
No, Apremilast is not an immunosuppressant. It belongs to a group of drugs called phosphodiesterase-4 (PDE4) inhibitors and exerts its effects by inhibiting the action of PDE4. PDE4 is present in inflammatory cells, and inhibiting its action reduces the molecules that cause inflammation.
How long do the effects of Apremilast last?
Apremilast is used to treat psoriasis vulgaris (red, scaly, thick, itchy, and painful skin lesions) and psoriatic arthritis (a disease that causes joint pain and swelling). It is a long-term treatment, and improvement may be seen after about 16 weeks.
Can Apremilast cause depression?
Yes, Apremilast 20 can cause depression as a side effect. Suicidal ideation may also occur. If you have a history of depression, avoid using this medication. If you experience any of these symptoms, consult a doctor immediately or ask a friend or relative to seek medical attention.
Does Apremilast tablets cause weight loss?
Yes, Apremilast tablets can cause loss of appetite, which may lead to further weight loss. Monitor your weight regularly while taking Apremilast 20 tablets. If you experience significant weight loss, consult your doctor and consider discontinuing Apremilast tablets.
How should I take Apremilast 20 tablets?
Follow your doctor’s instructions carefully. A low dose will be prescribed initially. After 6 days, the dose will be gradually increased. Swallow the tablets whole with water. They can be taken with or without food.
Can Apremilast 20 tablets be taken with rifampicin?
Do not take rifampicin while taking Apremilast tablets. Rifampicin inhibits the action of Apremilast, lowering its concentration and weakening its effect. Therefore, improvement may not be seen even after taking Apremilast.
What happens if I become pregnant while taking Apremilast 20?
If you become pregnant while taking Apremilast, consult your doctor immediately. Pregnancy should be avoided while taking this medication. This is because animal studies suggest that the use of Apremilast 20 may increase the risk of miscarriage and birth defects in the fetus.
Additional information
| Tablet/s | 40 Tablet/s, 80 Tablet/s, 160 Tablet/s |
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